ZFIN Image: Niu et al., 2012, Fig. 1

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Figure Caption

Fig. 1 The sq198 mutation confers hypoplastic digestive organs and malformed skeletal cartilage. (A–D) WISH using markers specifically for the liver (fabp10a) (A), exocrine pancreas (trypsin) (B), intestine (fabp2) (C), and endocrine pancreas (insulin) (D) on 3 dpf wildtype (WT) and mutant (mu) embryos. (E) Alcian blue staining showing the branchial arches 1–7 in WT and sq198 (mu) at 4 dpf. (F,G) Histochemical staining of alkaline phosphatase (AP) did not reveal obvious difference between 3 dpf wildtype (WT) and mutant (mu) blood vessels (F) whilst the head region of the pronephric ducts appears thinner in the mutant (G).

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Acknowledgments

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Reprinted from Developmental Biology, 367(2), Niu, X., Gao, C., Jan Lo, L., Luo, Y., Meng, C., Hong, J., Hong, W., and Peng, J., Sec13 safeguards the integrity of the endoplasmic reticulum and organogenesis of the digestive system in zebrafish, 197-207, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.