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Fig. 5
RA rescues hmx4 morphant phenotypes. Eye field narrowing (A–D), the neural tube closure defect (F–I), and loss of vagal motor neurons (K–N) in hmx4 morphants are rescued by treatment with 1 nM RA. Frequencies of morphant phenotypes are scored for eye field narrowing (E), open neural tube (J) and loss of vagal motor neurons (O). All rescues are statistically significant (see text for statistical tests). Error bars represent standard error.
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Reprinted from Developmental Biology, 355(1), Gongal, P.A., March, L.D., Holly, V.L., Pillay, L.M., Berry-Wynne, K.M., Kagechika, H., and Waskiewicz, A.J., Hmx4 regulates Sonic hedgehog signaling through control of retinoic acid synthesis during forebrain patterning, 55-64, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.