Image
|
Figure Caption
Fig. S6
(related to Figure 6). Ectopic expression of Cxcl12b induces abnormal migration of LECs
(A-D) Confocal images of trunk vessels in a 5 dpf Tg(fli-EGFP)y1 embryos expressing TagRFP-T and Cxcl12b in a subset of vISV endothelial cells. A red box in A indicates magnified area showing in B to D. (B) Green channel only. (C) Merged image. (D) Red channel only. Magenta arrowheads indicate ectopic Cxcl12b-expressing vISV endothelial cells. White arrowheads point to an adjacent ectopic vISV-aligned lymphatic segment.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Reprinted from Developmental Cell, 22(4), Cha, Y.R., Fujita, M., Butler, M., Isogai, S., Kochhan, E., Siekmann, A.F., and Weinstein, B.M., Chemokine Signaling Directs Trunk Lymphatic Network Formation along the Preexisting Blood Vasculature, 824-836, Copyright (2012) with permission from Elsevier. Full text @ Dev. Cell