ZFIN Image: Sultana et al., 2008, Fig. 1

Image

Figure Caption

Fig. 1

Progressive heart malformation in zebrafish ftk mutant. (A and B) Gross heart morphology of ftk mutant. Wild-type (A) and ftk mutant embryos (B) at 74 hpf. Arrowhead indicates heart perforations in the ftk mutant; arrow points to blood cells accumulated in the pericardiac cavity. (C–F) Sagittal sections of the heart. At 72 hpf (C and D), a dilated atrium (A) and ventricle (V) are evident in the ftk mutant. The cardiac muscles appear to be thinner (arrows in D), and the dilation of heart chambers is under way. At 120 hpf (E and F), the heart chamber dilation becomes more severe in ftk mutants with thinner ventricular and atrial walls. Red arrows indicate the valve leaflets. (Scale bars: 150 μm.)

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA