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Fig. 5 Epistatic interaction between miR-92 and gata5. (A-E) Localization of sox17-expressing cells in wild-type and variously injected zebrafish embryos at 90% epiboly. MO refers to miR-92 MO. Views are lateral with dorsal to the right. (F) Numbers of sox17-expressing cells in NICs (n=4), miR-92 gain-of-function (n=4), miR-92 and gata5 co-injected (n=7), miR-92 loss-of-function (n=4) and miR-92 MO and gata5 MO co-injected (n=7) embryos. Error bars represent s.e.m. *, P<0.01 between injected embryos and NIC; Student′s t-test. (G) Percentages of left (L), right (R), midline (M) and bilateral (B) localized cmlc2 in NIC (n=112), miR-92 gain-of-function (n=67) and miR-92 and gata5 co-injected (n=31) embryos. (H) Percentages of left, right, midline and bilateral localized cmlc2 in NIC (n=97), miR-92 loss-of-function (n=61) and miR-92 MO and gata5 MO co-injected (n=81) embryos.