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Fig. S2 Effect of small compounds on zebrafish larvae regeneration. Proliferating cells scored by anti-PH3 staining at 6 dpf / 1dpi. The number of proliferating cells is significantly enhanced by incubating regenerating larva in 20 μM SB203580 and 20 μM PD098059. In contrast, this number is significantly reduced in larva incubated in 20 μM SP600125, 5 μM Cyclopamine, 5 μM LY294002 or 10 μM PD168393. The images correspond to the region B as defined in Fig. 1D.
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Reprinted from Developmental Biology, 327(1), Rojas-Muñoz, A., Rajadhyksha, S., Gilmour, D., van Bebber, F., Antos, C., Rodríguez Esteban, C., Nüsslein-Volhard, C., and Izpisúa Belmonte, J.C., ErbB2 and ErbB3 regulate amputation-induced proliferation and migration during vertebrate regeneration, 177-190, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.