ZFIN Image: Insinna et al., 2010, Fig. 1

Image

Figure Caption

Fig. 1 The cnb mutation disrupts photoreceptor development. (A-D) Side (A, C) and dorsal (B, D) views of 5-dpf wild-type (A, B) and cnb mutant (C, D) embryos. (E-F) Retinal histology of wild-type (E) and cnb (F) retina at 4 dpf. (G, H) Zpr-1 immunoreactivity (brown) to label double cone photoreceptors (PhR) in 4-dpf wild-type (G) and cnb embryos (H). (I, J) ID1 immunoreactivity (brown) to label rod photoreceptors in 4-dpf wild-type (G) and cnb embryos (H). Nuclei in (G, H) are counterstained with methylene blue. (K-N) Confocal microscopy of wild-type (K, M) and cnb (L, N) whole retina (K, L) and individual rod photoreceptor cells (M, N) from Tg(Xlrho:EGFP)^fl1fish. Green, Xlrho:EGFP-positive cells; red, propidium iodide positive nuclei. Scale bars: 1 mm in (A, C); 40 μm in (E-L); 5 μm in (M, N). EGFP, enhanced green fluorescent protein.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Neural Dev.