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Fig. 9
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Fig. 9 Markers of Hedgehog signaling during uxs1 mutant endochondral ossification. (A–J) In situ hybridization on horizontal sections through 5 dpf ceratohyal for ihha (A, B), ihhb (C, D), ptc1 (E, F), ptc2 (G, H), and gli3 (I, J). Wild-type expression of ihha (A) and ihhb (B) appeared similar to that observed in uxs1hi3357 mutant chondrocytes (B, D). Compared to wild-type perichondrium (E, G, I), uxs1 mutant perichondrium demonstrated increased expression of ptc1 (F), ptc2 (H), and gli3 (J).
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Reprinted from Developmental Biology, 341(2), Eames, B.F., Singer, A., Smith, G.A., Wood, Z.A., Yan, Y.L., He, X., Polizzi, S.J., Catchen, J.M., Rodriguez-Mari, A., Linbo, T., Raible, D.W., and Postlethwait, J.H., UDP xylose synthase 1 is required for morphogenesis and histogenesis of the craniofacial skeleton, 400-415, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.