ZFIN Image: Yanicostas et al., 2009, Fig. 2

Image

Figure Caption

Fig. 2 Effects of anosmin-1a depletion on the differentiation of the olfactory epithelium and axon pathfinding of olfactory sensory neurons. Frontal views of living omp-tau::GFP zebrafish embryos at 24 (A–E), 48 (F–J) and 72 hpf (K–O). Wild-type embryos (A, F, K) and kal1a morphants (B–E, G–J, L–O). The same wild-type embryo (A, F, K) and kal1a morphants (B, G, L; C, H, M; D, I, N and E, J, O) were visualized at 24, 48, and 72 hpf. Dorsal is to the top, and ventral to the bottom. Large white arrow indicates tightly fasciculated OSN axons, small white arrows show defasciculated axon fibres within olfactory bulbs, red arrows indicate disorganized olfactory sensory axons and small green arrows point to dissociated olfactory sensory neurons. OE, olfactory epithelium; ON, olfactory nerve; OB, olfactory bulbs. Scale bar = 50 μm.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Molecular and Cellular Endocrinology, 312(1-2), Yanicostas, C., Herbomel, E., Dipietromaria, A., and Soussi-Yanicostas, N., Anosmin-1a is required for fasciculation and terminal targeting of olfactory sensory neuron axons in the zebrafish olfactory system, 53-60, Copyright (2009) with permission from Elsevier. Full text @ Mol. Cell. Endocrinol.