ZFIN Image: Picker et al., 2009, Fig. S9

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Figure Caption

Fig. S9 Effect of clonal dnFgfR1 overexpression on foxg1 and foxd1 in the evaginating optic vesicle. Clonal dnFgfr1 overexpression by transplantation and heat-shock induction of rhodamine-dextran lineage-labeled Tg (hsp70l:dnfgfr1-EGFP)pd1 cells. dnFgfr1 overexpression in the dorsal optic vesicle leaflet (arrowheads) represses foxg1 expression (A) and leads to ectopic foxd1 expression (B) at 12ss. Heat shocks were given at the onset of optic vesicle evagination (1-3ss). Top panels: dorsal views, bottom panels: cross-sections with dorsal to the top, left panels: bright field, right panels: fluorescent lineage label, and dotted lines: neural tube boundary (bottom panels) or optic vesicle boundary (top panels).

Acknowledgments

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