ZFIN Image: Picker et al., 2009, Fig. S7

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Figure Caption

Fig. S7 Live phenotype of Fgf8/3/24 mutant embryos at 28 h. (A) wt control embryo, (B) fgf8^-/- mutant with reduced ear and lacking cerebellum (arrowheads), (C) fgf3^-/- mutant with small lens (arrowhead), (D) fgf8^-/-; fgf3^+/- transheterozygous embryo, lacking the cerebellum and with strongly reduced ear (arrowheads), (E) fgf8/3^-/- double-mutant, lacking cerebellum and ear and with small lens (arrowheads), (F) fgf8/24^-/- double mutant, showing nasally tilted eye position, lack of the cerebellum, and reduction of the ear, (G) fgf8^-/-; fgf3^+/- transheterozygous embryo, injected with fgf24 MO (fgf8/24^-/-; fgf3^+/-), showing nasally tilted eye position, lack of the cerebellum, and strong reduction of the ear (arrowheads), (H) fgf8/3^-/- double mutant injected with fgf24 MO (fgf8/3/24^-/-), showing nasally tilted eye position, lack of the cerebellum and ear (arrowheads), and (I) wt embryos treated with FgfR-inh. (wt+FgfR-Inh.), showing nasally tilted eye position, lack of cerebellum, and reduced ear (arrowheads).

Acknowledgments

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