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Fig. 6 Mypt1 inhibits the Rho-Rock-Myosin pathway. (A,B) mypt1 morphant zebrafish embryos were treated with blebbistatin (A) or Rho kinase inhibitor III (B, Rock-I) and assayed for blebbing activity by time-lapse microscopy at bud stage. s, seconds. (C)ca-rhoA mRNA results in excessive blebbing of lateral mesoderm at shield stage. (D,E) Quantification of data in A and B (D) and C (E). The y-axis shows the number of blebs per cell per hour. **, P<0.01.
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