ZFIN Image: Málaga-Trillo et al., 2009, Fig. 7

Image

Figure Caption

Fig. 7 Radial Intercalation in Control and PrP-1 Morphant Embryos

Cell movements in lateral regions of the epiblast (8 hpf) were imaged over 20 min using Nomarski optics. (Time in minutes and seconds is shown in the lower-right corner of each panel.) Selected frames from time-lapse video recordings were pseudocolored: intercalating and surrounding cells are shown in blue and green, respectively (after Kane et al. [22]), and cells forming new contacts are shown in red.

(A) In control embryos, cells from the interior layer (blue) intercalate among cells in the exterior layer (green) and establish additional cell contacts with other cells (red).

(B) In PrP-1 morphant embryos, cells from the interior layer often intercalate and then deintercalate, thereby failing to maintain attachment to cells from the exterior layer (green cells 2 and 4, and red cells).

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Biol.