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Fig. 2 smp transcription is not activated during wound healing. (A) Small 0.2–0.7 mm incisions (red arrows) between the bony fin rays (yellow dots) result in a wound closure response associated with the activation of mmp9 (green arrowhead), a gene activated during wound healing, by 6 h post injury (hpi). (B) Sense control of mmp9 lacks any staining. (C) smp gene transcription is not detected at 6 hpi, (D) 12 hpi, or (E) 24 hpi. By 24 hpi, the superficial wound incision has healed. All scale bars equal 100 μm.
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Reprinted from Developmental Biology, 325(2), Kizil, C., Otto, G.W., Geisler, R., Nüsslein-Volhard, C., and Antos, C.L., Simplet controls cell proliferation and gene transcription during zebrafish caudal fin regeneration, 329-340, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.