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Fig. S12 Sdf1a Signaling Is Not Necessary for Local Activation of the Wnt/β-Catenin Pathway in the Primordium
In situ hybridization with axin2 reveals that activation of the Wnt/β-catenin pathway in the leading zone occurs normally in 26hpf sdf1a morphant primordia (A and B). The sdf1a morphant primordium has not started to migrate and is still posterior to the otic capsule.
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Reprinted from Developmental Cell, 15(5), Aman, A., and Piotrowski, T., Wnt/beta-catenin and Fgf signaling control collective cell migration by restricting chemokine receptor expression, 749-761, Copyright (2008) with permission from Elsevier. Full text @ Dev. Cell