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Fig. S10 In WT Embryos dkk1 Is Expressed Immediately Adjacent to the Leading Zone in which Wnt/β-Catenin Signaling Is Active
Double in situ hybridization with dkk1 and the Wnt/β-catenin target lef1 at 32hpf reveals that Wnt/β-catenin signaling is not inhibited in cells immediately adjacent to dkk1 expressing cells.
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Reprinted from Developmental Cell, 15(5), Aman, A., and Piotrowski, T., Wnt/beta-catenin and Fgf signaling control collective cell migration by restricting chemokine receptor expression, 749-761, Copyright (2008) with permission from Elsevier. Full text @ Dev. Cell