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Fig. S5 sef Knockdown Leads to Ectopic Expression of dkk1 in the Leading Zone
(A) dkk1 is expressed in a region immediately adjacent to the leading zone in wt primordia.
(B) In primordia of 26hpf sef morphant embryos dkk1 is ectopically expressed in tip zone cells consistent with a role for sef in repressing Fgf signaling in these cells.
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Reprinted from Developmental Cell, 15(5), Aman, A., and Piotrowski, T., Wnt/beta-catenin and Fgf signaling control collective cell migration by restricting chemokine receptor expression, 749-761, Copyright (2008) with permission from Elsevier. Full text @ Dev. Cell