ZFIN Image: Huang et al., 2003, Fig. 4

Image

Figure Caption

Fig. 4 Intervessel pruning. Following plexus remodeling, the proximal regenerate undergoes intervessel pruning. In 5-dpa (A) and 11-dpa (B) TG(fli1:EGFP)^y1 regenerates, the number of intervessel commissures in the regenerate (yellow arrowheads) is significantly higher than in the stump (white arrowheads) or in the normal fin (C). The yellow double-headed arrow delineates the plexus. (D) Intervessel commissure density in a regenerating fin. Intervessel commissures reach a maximal density at 5 dpa (30 commissures/mm) and are gradually pruned back to the density of a normal fin (∼10 commissures/mm, 0 dpa). Scale bar, 200 μm.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 264(1), Huang, C., Lawson, N.D., Weinstein, B.M., and Johnson, S.L., reg6 is required for branching morphogenesis during blood vessel regeneration in zebrafish caudal fins, 263-274, Copyright (2003) with permission from Elsevier. Full text @ Dev. Biol.