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Fig. 9 Esophageal development is perturbed by loss of hedgehog signaling. (A–C) Cross-sections through the esophagus of wild-type (A), syu (B), and yto (C) 74-hpf larvae with corresponding schematics (D–F). The wild-type esophagus is comprised of a folded epithelium surrounded by mesenchyme. The swimbladder pneumatic duct (*) branches from the esophagus (arrow) at this level. By contrast, the syu (B) and yto (C) esophagus (arrow) is dysmorphic and binds minimal fluorescent soybean agglutinin (H, I), an epithelial differentiation marker, compared with wild-types (G).
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Reprinted from Developmental Biology, 255(1), Wallace, K.N. and Pack, M., Unique and conserved aspects of gut development in zebrafish, 12-29, Copyright (2003) with permission from Elsevier. Full text @ Dev. Biol.