ZFIN Image: Dee et al., 2008, Fig. 7

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Fig. 7 Sox3 knock-down does not affect rostrocaudal patterning of the CNS. Control (A–E) and sox3 morphant (F–J) embryos were stained for the expression of positional markers of the developing brain and spinal cord. Expression of positional markers is maintained in morphant embryos despite severe disruption of CNS tissue. Markers used are emx1 (A, F, 42/49 embryos), otx2 (B, G, 10/10), pax2a (arrows indicate midbrain/hindbrain boundary; C, H, 19/22), krox20 (D, I, 14/14) and hoxb1b (arrows indicate rostral limit of CNS expression; E, J, 23/23). All embryos are aged 24 hpf and dorsal view except for panels E and J which are lateral view.

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Acknowledgments

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Reprinted from Developmental Biology, 320(1), Dee, C.T., Hirst, C.S., Shih, Y.H., Tripathi, V.B., Patient, R.K., and Scotting, P.J., Sox3 regulates both neural fate and differentiation in the zebrafish ectoderm, 289-301, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.