ZFIN Image: Lee et al., 2006, Fig. 5

Image

Figure Caption

Fig. 5 blimp-1 acts downstream of tbx5 and fgf24. (A-F) tbx5 expression in the fin buds (arrows) of wild-type and blimp-1 morphants. (G and H) fgf24 expression (arrows) in a wild-type embryo and a blimp-1 morphant. (I) A wild-type fin, showing fgf24 expression in the AER (arrow). (J) A blimp-1 morphant at the same stage, showing absence of fgf24 from the ectoderm (black arrow) and its continued expression in the mesenchyme (white arrow). (K and L) blimp-1 expression is absent (arrows) from the prospective fin buds of tbx5 and fgf24 MO injected embryos. All panels depict dorsal views, except panels I and J, which depict lateral views.

Figure Data

Expression / Labeling details

Acknowledgments

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Reprinted from Developmental Biology, 300(2), Lee, B.C., and Roy, S., Blimp-1 is an essential component of the genetic program controlling development of the pectoral limb bud, 623-634, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.