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Fig. 4 Cell-cycle exit of retinal progenitors was impaired in zRab11-FIP4 morphants. (A) Cells in cell cycle were analyzed by BrdU labeling (54 to 60 hpf) and immunostaining for pHisH3 (60 hpf). (B) The expression of cyclin D1 and p57kip2 in the retina was analyzed by in situ hybridization at 37 and 45 hpf. Expression of p57kip2 at the peripheral region of the control retina at 45 hpf are pointed out by an arrowhead. The position of CMZ is marked with a bracket. Scale bars indicate 50 μm.
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Reprinted from Developmental Biology, 292(1), Muto, A., Arai, K.I., and Watanabe, S., Rab11-FIP4 is predominantly expressed in neural tissues and involved in proliferation as well as in differentiation during zebrafish retinal development, 90-102, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.