Fig. 1

Fig. 1 Mutations Specific to Melanocyte Regeneration (A–F) eartha^j23e1 (C) and julie^j24e1 mutants (E) both develop larval melanocyte patterns nearly identical to wild-type larvae (A), although melanocytes in eartha^j23e1 mutants appear to have lighter pigmentation than that in the wild-type larvae. Upon larval melanocyte ablation by MoTP (14–72 hpf), wild-type larvae (B) regenerate many melanocytes at 5 dpf (arrowhead in [B]), while eartha^j23e1 (arrowhead in [D]) and julie^j24e1 (arrowhead in [F]) mutants largely fail to regenerate melanocytes. Additional phenotypes are indicated by an arrow in (C) marking a shortened pharyngeal skeleton in eartha^j23e1 mutants and by an arrow in (E) indicating small eyes and head in julie^j24e1 mutants. (G–H) The numbers of melanocytes in the untreated (G) and MoTP-treated (H) wild-type and mutant larvae at 5 dpf. Scale bar: 300 μm.