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Fig. 3 Identification of 2 Nodal-repressed genes. (A) The Venn diagram indicates the number of identified Sqt-down (red) and Oep-up (blue) clones. The overlap (orange) is indicated. Overlapping clones were screened by ISH. Two Nodal-repressed genes, sox2 and sox3, were identified. (B) Expression patterns of sox2 and sox3. The top two images are cartoon representations; the bottom two images are whole-mount ISH of sox3. Genotypes are indicated. Arrows indicate the region that lacks expression in wild type.
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Reprinted from Developmental Biology, 304(2), Bennett, J.T., Joubin, K., Cheng, S., Aanstad, P., Herwig, R., Clark, M., Lehrach, H., and Schier, A.F., Nodal signaling activates differentiation genes during zebrafish gastrulation, 525-540, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.