ZFIN Image: Hans et al., 2007, Fig. 1

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Figure Caption

Fig. 1 Otic vesicle size is affected by the overexpression of fgf8 depending on the developmental stage. (A, B) Overexpression of fgf8 by mRNA injections at the 1-cell stage completely ablates all indications of otic fate (27/40 embryos, B) in comparison to wild-type vesicles (A). (C-E) Misexpression of fgf8 at 30% epiboly (28/28 embryos, C), shield stage (27/28 embryos, D) and 75% epiboly (29/29 embryos, E) results in smaller otic vesicles. (F-H) Otic vesicles are increased in size if fgf8 is misexpressed at the tailbud (26/29 embryos, F) or the 4-somite stage (24/28 embryos, G) whereas at the 8-somite stage no change in vesicle size is observed (26/26 embryos, H). Lateral views of otic vesicles highlighted with starmaker at 24h with anterior to the left and dorsal towards the top. Scale bar: 30 μm.

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Dev. Biol.