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Fig. S3 Induction of sox17 in response to overexpression of Cas-WT or Cas-S47A RNAs injected at 10 ng/ml into one animal blastomere at the 16-cell stage. (A-C) Results of three independent experiments. (D,E) Co-injection with ERK* RNA at 50 ng/ml decreases the ability of Cas-WT to induce sox17 (D). However, Cas-S47A is insensitive to overexpression of ERK2* (E).
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