ZFIN Image: Norton et al., 2005, Fig. 6

Image

Figure Caption

Fig. 6 Floorplate phenotypes in mol^-/- embryos are not only due to reduced Hh activity. (A,B) Lateral views of wild-type and mol^-/- embryos following overexpression of exogenous shh. There is some dorsal expansion (arrowheads) of foxa expression in the midbrain of both the wild-type and the mol^-/- embryo; however, foxa expression remains discontinuous and narrow along the CNS midline of the mol^-/- embryo (asterisks in B). (C,D) Transverse sections of embryos in which wild-type cells were transplanted into the prospective floorplate of a mol^-/- embryo (C) or mol^-/- cells were transplanted into the prospective floorplate of a wild-type embryo (D). foxa is shown in blue and transplanted cells are stained brown.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development