Gene

sema3d

ID

ZDB-GENE-990715-2

Name

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D

Symbol

sema3d Nomenclature History

Previous Names

sema2
sema3D (1)
semaZ2 (1)

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Exhibits neuropilin binding activity. Involved in several processes, including animal organ development; fin regeneration; and nervous system development. Predicted to localize to extracellular space and integral component of plasma membrane. Is expressed in several structures, including central nervous system; hindbrain neural keel; neural crest; notochord; and posterior lateral line system. Orthologous to human SEMA3D (semaphorin 3D).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

49 figures from 23 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

eu640 (23 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 10 figures from 5 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sema3d Human Ortholog

No data available

Associated With sema3d Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001627	Sema domain
Domain	IPR016201	PSI domain
Domain	IPR042582	Semaphorin-3D, Sema domain
Family	IPR027231	Semaphorin
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily
Homologous_superfamily	IPR036352	Sema domain superfamily