Gene

nr2f5

ID
ZDB-GENE-990415-253
Name
nuclear receptor subfamily 2, group F, member 5
Symbol
nr2f5 Nomenclature History
Previous Names
  • COUP
  • couptf
  • COUPTFgamma (1)
  • svp46 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in cranial skeletal system development and response to retinoic acid. Predicted to localize to nucleus. Is expressed in several structures, including anterior neural keel; hindbrain neural keel; mesoderm; nervous system; and pharyngeal arch.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
20 figures from 10 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Okeke et al., 2022
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nr2f5 Human Ortholog
No data available
Associated With nr2f5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000536 Nuclear hormone receptor, ligand-binding domain
Domain IPR001628 Zinc finger, nuclear hormone receptor-type
Family IPR001723 Nuclear hormone receptor
Family IPR050274 Nuclear hormone receptor family NR2 subfamily
Homologous_superfamily IPR013088 Zinc finger, NHR/GATA-type
Homologous_superfamily IPR035500 Nuclear hormone receptor-like domain superfamily
Domain Details Per Protein
Protein Length Nuclear hormone receptor Nuclear hormone receptor family NR2 subfamily Nuclear hormone receptor, ligand-binding domain Nuclear hormone receptor-like domain superfamily Zinc finger, NHR/GATA-type Zinc finger, nuclear hormone receptor-type
UniProtKB:B3DI15 403
UniProtKB:Q06726 403
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA nr2f5-201 (1) Ensembl 3,077 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations