Gene
cdh11
- ID
- ZDB-GENE-980526-170
- Name
- cadherin 11, type 2, OB-cadherin (osteoblast)
- Symbol
- cdh11 Nomenclature History
- Previous Names
-
- cdhvn
- ventral neural cadherin
- vnc
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have cadherin binding activity; calcium ion binding activity; and cytoskeletal protein binding activity. Involved in otolith development; retina development in camera-type eye; and retinal ganglion cell axon guidance. Predicted to localize to adherens junction; catenin complex; and cell surface. Human ortholog(s) of this gene implicated in Elsahy-Waters syndrome. Is expressed in cleithrum; nervous system; optic vesicle; and pectoral fin bud. Orthologous to human CDH11 (cadherin 11).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 11 figures from 2 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Elsahy-Waters syndrome | Alliance | Elsahy-Waters syndrome | 211380 |
| Teebi hypertelorism syndrome 2 | Alliance | Teebi hypertelorism syndrome 2 | 619736 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cadherin | Cadherin conserved site | Cadherin-like | Cadherin-like superfamily | Cadherin, Y-type LIR-motif | Catenin binding domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:B3DGG4
|
800 |
Interactions and Pathways
No data available
Plasmids
No data available