Gene
kcnt2b
- ID
- ZDB-GENE-231129-4
- Name
- potassium sodium-activated channel subfamily T member 2b
- Symbol
- kcnt2b Nomenclature History
- Previous Names
-
- CR392045.1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable intracellular sodium-activated potassium channel activity and outward rectifier potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to act upstream of or within monoatomic ion transmembrane transport and potassium ion transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in caudal tuberculum; hindbrain; hypothalamus; thalamus; and ventral telencephalon. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 57. Orthologous to human KCNT2 (potassium sodium-activated channel subfamily T member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Silic et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| developmental and epileptic encephalopathy 57 | Alliance | Developmental and epileptic encephalopathy 57 | 617771 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003929 | Calcium-activated potassium channel BK, alpha subunit |
| Domain | IPR013099 | Potassium channel domain |
| Domain | IPR055153 | Calcium-activated potassium channel slowpoke-like, RCK domain |
| Family | IPR047871 | Calcium-activated potassium channel slowpoke-like |
| Homologous_superfamily | IPR036291 | NAD(P)-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Calcium-activated potassium channel BK, alpha subunit | Calcium-activated potassium channel slowpoke-like | Calcium-activated potassium channel slowpoke-like, RCK domain | NAD(P)-binding domain superfamily | Potassium channel domain |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3B8J5 | InterPro | 1231 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids