Gene

kcnt1b

ID

ZDB-GENE-141210-6

Name

potassium sodium-activated channel subfamily T member 1b

Symbol

kcnt1b Nomenclature History

Previous Names

si:dkey-21e5.1

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have intracellular sodium activated potassium channel activity and outward rectifier potassium channel activity. Predicted to be involved in potassium ion transport. Predicted to localize to integral component of membrane and plasma membrane.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Silic et al., 2021

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kcnt1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
autosomal dominant nocturnal frontal lobe epilepsy 5	Alliance	Epilepsy nocturnal frontal lobe, 5	615005
developmental and epileptic encephalopathy 14	Alliance	Developmental and epileptic encephalopathy 14	614959

Associated With kcnt1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003929	Calcium-activated potassium channel BK, alpha subunit
Domain	IPR013099	Potassium channel domain
Family	IPR047871	Calcium-activated potassium channel slowpoke-like
Homologous_superfamily	IPR036291	NAD(P)-binding domain superfamily

Domain Details Per Protein

Protein	Length	Calcium-activated potassium channel BK, alpha subunit	Calcium-activated potassium channel slowpoke-like	NAD(P)-binding domain superfamily	Potassium channel domain
UniProtKB:A0A8M9PZ66 InterPro	1261
UniProtKB:A0A8M9QEY3 InterPro	1254
UniProtKB:A0A8M9Q4Y2 InterPro	1260
UniProtKB:A0A8M9PZ72 InterPro	1240
UniProtKB:A0A8M9Q9W1 InterPro	1247
UniProtKB:A0A8M9PLK9 InterPro	1219

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	kcnt1-202 (1) Ensembl	Ensembl	3,321 nt	Select Tool ZFIN BLAST
mRNA	kcnt1-204 (1) Ensembl	Ensembl	3,363 nt	Select Tool ZFIN BLAST
mRNA	kcnt1b-201 (1) Ensembl	Ensembl	3,385 nt	Select Tool ZFIN BLAST
mRNA	kcnt1b-203 (1) Ensembl	Ensembl	2,037 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

Addgene:164962

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations