Gene
kcnn4
- ID
- ZDB-GENE-131127-192
- Name
- potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
- Symbol
- kcnn4 Nomenclature History
- Previous Names
-
- si:dkeyp-84f3.3 (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have calmodulin binding activity and small conductance calcium-activated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to localize to neuron projection; neuronal cell body; and plasma membrane. Human ortholog(s) of this gene implicated in dehydrated hereditary stomatocytosis 2. Orthologous to human KCNN4 (potassium calcium-activated channel subfamily N member 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Silic et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| dehydrated hereditary stomatocytosis 2 | Alliance | Dehydrated hereditary stomatocytosis 2 | 616689 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Calmodulin-binding domain | Potassium channel, calcium-activated, SK | Potassium channel domain | SK, calmodulin-binding domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:X1WCL6
|
481 |
Interactions and Pathways
No data available
Plasmids