Gene
kcnn4
- ID
- ZDB-GENE-131127-192
- Name
- potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
- Symbol
- kcnn4 Nomenclature History
- Previous Names
-
- si:dkeyp-84f3.3 (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable Intermediate conductance calcium-activated potassium channel activity and calmodulin binding activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to act upstream of or within potassium ion transport. Predicted to be located in membrane. Predicted to be active in neuron projection; neuronal cell body; and plasma membrane. Human ortholog(s) of this gene implicated in dehydrated hereditary stomatocytosis 2. Orthologous to human KCNN4 (potassium calcium-activated channel subfamily N member 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Silic et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| dehydrated hereditary stomatocytosis 2 | Alliance | Dehydrated hereditary stomatocytosis 2 | 616689 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Calmodulin-binding domain | Potassium channel, calcium-activated, SK | Potassium channel domain | SK, calmodulin-binding domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:X1WCL6
|
481 |
Interactions and Pathways
No data available
Plasmids