Gene
cxcl8b.3
- ID
- ZDB-GENE-111004-1
- Name
- chemokine (C-X-C motif) ligand 8b, duplicate 3
- Symbol
- cxcl8b.3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable CXCR chemokine receptor binding activity and chemokine activity. Predicted to be involved in several processes, including antimicrobial humoral immune response mediated by antimicrobial peptide; cellular response to lipopolysaccharide; and neutrophil chemotaxis. Predicted to act upstream of or within several processes, including chemotaxis; defense response; and neutrophil activation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including acute pyelonephritis; autoimmune uveitis; gastritis (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human CXCL8 (C-X-C motif chemokine ligand 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Dennhag et al., 2024
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Chemokine beta/gamma/delta | Chemokine interleukin-8-like domain | Chemokine interleukin-8-like superfamily | CXC Chemokine domain |
|---|---|---|---|---|---|
|
UniProtKB:A9ZPF0
|
117 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cxcl8b.3-201
(1)
|
Ensembl | 2,130 nt |
Interactions and Pathways
No data available
Plasmids
No data available