Gene

kcnc3a

ID
ZDB-GENE-100901-1
Name
potassium voltage-gated channel, Shaw-related subfamily, member 3a
Symbol
kcnc3a Nomenclature History
Previous Names
  • kv3.3 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Exhibits voltage-gated potassium channel activity. Involved in motor neuron axon guidance. Predicted to localize to several cellular components, including dendrite membrane; neuronal cell body membrane; and voltage-gated potassium channel complex. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 13. Is expressed in Purkinje cell. Orthologous to human KCNC3 (potassium voltage-gated channel subfamily C member 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kcnc3a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
spinocerebellar ataxia type 13 Alliance Spinocerebellar ataxia 13 605259
Associated With kcnc3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000210 BTB/POZ domain
Domain IPR003131 Potassium channel tetramerisation-type BTB domain
Domain IPR005821 Ion transport domain
Family IPR003968 Potassium channel, voltage dependent, Kv
Family IPR003974 Potassium channel, voltage dependent, Kv3
Homologous_superfamily IPR011333 SKP1/BTB/POZ domain superfamily
Homologous_superfamily IPR027359 Voltage-dependent channel domain superfamily
Domain Details Per Protein
Protein Length BTB/POZ domain Ion transport domain Potassium channel tetramerisation-type BTB domain Potassium channel, voltage dependent, Kv Potassium channel, voltage dependent, Kv3 SKP1/BTB/POZ domain superfamily Voltage-dependent channel domain superfamily
UniProtKB:A0A8M9PW22 626
UniProtKB:A0A8M9P777 666
UniProtKB:A0A8M3AQN6 636
UniProtKB:A0A8M3B8C3 609
UniProtKB:E1AZA4 642
UniProtKB:E1AZA5 659
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA kcnc3a-201 (1) Ensembl 2,320 nt
mRNA kcnc3a-202 (1) Ensembl 1,929 nt
mRNA kcnc3a-203 (1) Ensembl 2,080 nt
mRNA kcnc3a-204 (1) Ensembl 1,980 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-kcnc3a Rabbit
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations