Gene
tnfsf11
- ID
- ZDB-GENE-090805-2
- Name
- TNF superfamily member 11
- Symbol
- tnfsf11 Nomenclature History
- Previous Names
-
- RANKL (1)
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable tumor necrosis factor receptor binding activity. Acts upstream of or within response to mechanical stimulus. Predicted to be located in membrane. Is expressed in head and scale. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 2 and osteoporosis. Orthologous to human TNFSF11 (TNF superfamily member 11).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 11 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive osteopetrosis 2 | Alliance | Osteopetrosis, autosomal recessive 2 | 259710 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Tumour necrosis factor domain | Tumour necrosis factor-like domain superfamily |
|---|---|---|---|
|
UniProtKB:E7F3U1
|
251 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tnfsf11-201
(1)
|
Ensembl | 1,548 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-tnfsf11 | polyclonal | IgG | Rabbit |
|
Abcam plc
|
2 |
Plasmids
No data available