Gene

esama

ID

ZDB-GENE-090629-1

Name

endothelial cell adhesion molecule a

Symbol

esama Nomenclature History

Previous Names

esam
zESAMa (1)
sc:d0254

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Involved in cell adhesion involved in sprouting angiogenesis and platelet aggregation. Predicted to localize to integral component of membrane. Is expressed in several structures, including angioblastic mesenchymal cell; cardiovascular system; epiphysis; otic vesicle; and ventral mesoderm. Orthologous to human ESAM (endothelial cell adhesion molecule).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

13 figures from 6 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cssl:d0254 (18 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With esama Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental disorder with intracranial hemorrhage, seizures, and spasticity	620371

Associated With esama Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003598	Immunoglobulin subtype 2
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013106	Immunoglobulin V-set domain
Family	IPR042757	Endothelial cell-selective adhesion molecule
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily