Gene
frem1a
- ID
- ZDB-GENE-081119-1
- Name
- Fras1 related extracellular matrix 1a
- Symbol
- frem1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Involved in fin morphogenesis. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in congenital diaphragmatic hernia. Is expressed in fin fold pectoral fin bud; median fin fold; pectoral fin; pharyngeal arch; and trunk. Orthologous to human FREM1 (FRAS1 related extracellular matrix 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 17 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001304 | C-type lectin-like |
| Domain | IPR003644 | Na-Ca exchanger/integrin-beta4 |
| Domain | IPR045658 | FRAS1-related extracellular matrix protein, N-terminal domain |
| Family | IPR051561 | FRAS1-related extracellular matrix |
| Homologous_superfamily | IPR016186 | C-type lectin-like/link domain superfamily |
| Homologous_superfamily | IPR016187 | C-type lectin fold |
| Homologous_superfamily | IPR038081 | CalX-like domain superfamily |
| Repeat | IPR039005 | CSPG repeat |
Domain Details Per Protein
| Protein | Length | CalX-like domain superfamily | CSPG repeat | C-type lectin fold | C-type lectin-like | C-type lectin-like/link domain superfamily | FRAS1-related extracellular matrix | FRAS1-related extracellular matrix protein, N-terminal domain | Na-Ca exchanger/integrin-beta4 |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:D7PS89
|
2167 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available