Gene

ranbp2

ID

ZDB-GENE-081104-93

Name

RAN binding protein 2

Symbol

ranbp2 Nomenclature History

Previous Names

nup358 (1)
si:ch1073-55a19.2

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to contribute to GTPase activator activity. Predicted to be involved in NLS-bearing protein import into nucleus. Predicted to localize to cytoplasm and nuclear pore.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Magre et al., 2019

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Magre et al., 2019
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ranbp2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		{Encephalopathy, acute, infection-induced, 3, susceptibility to}	608033

Associated With ranbp2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR020892	Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
Domain	IPR000156	Ran binding domain
Domain	IPR001876	Zinc finger, RanBP2-type
Domain	IPR002130	Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
Domain	IPR022011	Nup358/RanBP2 E3 ligase domain
Family	IPR045255	Ran binding protein RanBP1-like
Homologous_superfamily	IPR011990	Tetratricopeptide-like helical domain superfamily
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR029000	Cyclophilin-like domain superfamily
Homologous_superfamily	IPR036443	Zinc finger, RanBP2-type superfamily
Repeat	IPR019734	Tetratricopeptide repeat

Domain Details Per Protein

Protein	Length	Cyclophilin-like domain superfamily	Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site	Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain	Nup358/RanBP2 E3 ligase domain	PH-like domain superfamily	Ran binding domain	Ran binding protein RanBP1-like	Tetratricopeptide-like helical domain superfamily	Tetratricopeptide repeat	Zinc finger, RanBP2-type	Zinc finger, RanBP2-type superfamily
UniProtKB:A0A8M9QJW3 InterPro	2984
UniProtKB:A0A8M1RKE0 InterPro	2958
UniProtKB:A0A8M9QFP1 InterPro	2968

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	ranbp2-202 (1) Ensembl	Ensembl		8,862 nt	Select Tool ZFIN BLAST
mRNA	ranbp2-203 (1) Ensembl	Ensembl		9,214 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-ranbp2	polyclonal	ranbp2		Rabbit	IHC WB		1

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations