Gene

mical1

ID

ZDB-GENE-081022-3

Name

microtubule associated monooxygenase, calponin and LIM domain containing 1

Symbol

mical1 Nomenclature History

Previous Names

zgc:171928

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to have FAD binding activity; actin binding activity; and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen. Predicted to be involved in actin filament depolymerization and sulfur oxidation. Predicted to localize to cytoplasm. Orthologous to human MICAL1 (microtubule associated monooxygenase, calponin and LIM domain containing 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Xue et al., 2010

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mical1 Human Ortholog

No data available

Associated With mical1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001715	Calponin homology domain
Domain	IPR001781	Zinc finger, LIM-type
Domain	IPR002938	FAD-binding domain
Domain	IPR022735	bMERB domain
Family	IPR050540	F-actin Monooxygenase Mical
Homologous_superfamily	IPR036188	FAD/NAD(P)-binding domain superfamily
Homologous_superfamily	IPR036872	CH domain superfamily

Domain Details Per Protein

Protein	Length	bMERB domain	Calponin homology domain	CH domain superfamily	F-actin Monooxygenase Mical	FAD-binding domain	FAD/NAD(P)-binding domain superfamily	Zinc finger, LIM-type
UniProtKB:E7F9T0 InterPro
UniProtKB:E5F2M3 InterPro	847
UniProtKB:G0WKK0 InterPro	322
UniProtKB:A0A9U5FS91 InterPro	1214

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	mical1-202 (1) Ensembl	Ensembl	3,920 nt	Select Tool
mRNA	mical1-203 (1) Ensembl	Ensembl	4,002 nt	Select Tool ZFIN BLAST
mRNA	mical1-204 (1) Ensembl	Ensembl	4,513 nt	Select Tool ZFIN BLAST
ncRNA	mical1-002 (1) Ensembl	Ensembl	1,212 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations