Gene
dkk2
- ID
- ZDB-GENE-080204-14
- Name
- dickkopf WNT signaling pathway inhibitor 2
- Symbol
- dkk2 Nomenclature History
- Previous Names
-
- zgc:171574
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have co-receptor binding activity and receptor antagonist activity. Involved in liver development and neuromast development. Predicted to localize to extracellular space. Is expressed in lateral plate mesoderm; midbrain hindbrain boundary; otic vesicle; and sensory system. Orthologous to human DKK2 (dickkopf WNT signaling pathway inhibitor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Wada et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR006796 | Dickkopf, N-terminal cysteine-rich |
| Domain | IPR047302 | Dickkopf-related protein 2, second cysteine-rich domain |
| Domain | IPR047303 | Dickkopf-related protein 2, first cysteine-rich domain |
| Domain | IPR048499 | Dickkopf-related protein 1/2/4, C-terminal subdomain 2 |
| Domain | IPR048500 | Dickkopf-related protein 1/2/4, C-terminal subdomain 1 |
| Family | IPR039863 | Dickkopf related protein 1-4 |
Domain Details Per Protein
| Protein | Length | Dickkopf, N-terminal cysteine-rich | Dickkopf-related protein 1/2/4, C-terminal subdomain 1 | Dickkopf-related protein 1/2/4, C-terminal subdomain 2 | Dickkopf related protein 1-4 | Dickkopf-related protein 2, first cysteine-rich domain | Dickkopf-related protein 2, second cysteine-rich domain |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A8KB56
|
243 |
Interactions and Pathways
No data available
Plasmids
No data available