Gene
ift70
- ID
- ZDB-GENE-070117-2066
- Name
- intraflagellar transport 70
- Symbol
- ift70 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Enables tubulin-glycine ligase activity. Involved in intraciliary transport and protein polyglutamylation. Acts upstream of or within several processes, including cilium assembly; establishment of planar polarity; and opsin transport. Located in axonemal microtubule and motile cilium. Is expressed in Kupffer's vesicle; lateral mesoderm; nervous system; and pronephros. Orthologous to human TTC30A (tetratricopeptide repeat domain 30A) and TTC30B (tetratricopeptide repeat domain 30B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 18 figures from 8 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR039941 | Tetratricopeptide repeat protein 30 |
| Homologous_superfamily | IPR011990 | Tetratricopeptide-like helical domain superfamily |
| Homologous_superfamily | IPR036723 | Alpha-catenin/vinculin-like superfamily |
| Repeat | IPR013105 | Tetratricopeptide repeat 2 |
| Repeat | IPR019734 | Tetratricopeptide repeat |
Domain Details Per Protein
| Protein | Length | Alpha-catenin/vinculin-like superfamily | Tetratricopeptide-like helical domain superfamily | Tetratricopeptide repeat | Tetratricopeptide repeat 2 | Tetratricopeptide repeat protein 30 |
|---|---|---|---|---|---|---|
|
UniProtKB:A7YE96
|
651 | |||||
|
UniProtKB:A0A8M9PR90
|
575 | |||||
|
UniProtKB:A0A8M9P934
|
645 | |||||
|
UniProtKB:A0A8M9PYI9
|
667 |
Interactions and Pathways
No data available
Plasmids
No data available