Gene

fev

ID

ZDB-GENE-070112-1852

Name

FEV transcription factor, ETS family member

Symbol

fev Nomenclature History

Previous Names

Pet-1 (1)
zgc:158720

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Exhibits transcription regulatory region sequence-specific DNA binding activity. Involved in hematopoietic stem cell differentiation and regulation of transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in several structures, including endothelial cell; hindbrain; pancreatic bud; presumptive blood; and serotonergic neurons. Orthologous to human FEV (FEV transcription factor, ETS family member).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

15 figures from 10 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fev Human Ortholog

No data available

Associated With fev Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000418	Ets domain
Family	IPR046328	ETS family
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036390	Winged helix DNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Ets domain	ETS family	Winged helix DNA-binding domain superfamily	Winged helix-like DNA-binding domain superfamily
UniProtKB:A0A8M9QJU5 InterPro	214
UniProtKB:A0A8M9QFM3 InterPro	162
UniProtKB:A3FEM2 InterPro	235
UniProtKB:A1L294 InterPro	162

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	fev-202 (1) Ensembl	Ensembl	1,366 nt	Select Tool
mRNA	fev-203 (1) Ensembl	Ensembl	1,305 nt	Select Tool
mRNA	fev-204 (1) Ensembl	Ensembl	491 nt	Select Tool ZFIN BLAST
ncRNA	fev-003 (1) Ensembl	Ensembl	959 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-fev	polyclonal	fev		Rabbit			2

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations