Gene

cd209

ID

ZDB-GENE-061207-22

Name

CD209 molecule

Symbol

cd209 Nomenclature History

Previous Names

DC-SIGN (1)
si:ch211-214k5.1
si:ch211-224h1.3

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have carbohydrate binding activity. Involved in T cell activation involved in immune response; adaptive immune response; and dendritic cell antigen processing and presentation. Localizes to cell surface. Human ortholog(s) of this gene implicated in Coronavirus infection; aspergillosis; dengue disease; human immunodeficiency virus infectious disease; and tuberculosis. Is expressed in several structures, including heart; immune system; integument; liver; and pleuroperitoneal region. Orthologous to several human genes including CLEC6A (C-type lectin domain containing 6A); CLEC4A (C-type lectin domain family 4 member A); and CLEC4C (C-type lectin domain family 4 member C).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cd209 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		{Dengue fever, protection against}	614371
		{HIV type 1, susceptibility to}	609423
		{Mycobacterium tuberculosis, susceptibility to}	607948

Associated With cd209 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018378	C-type lectin, conserved site
Domain	IPR001304	C-type lectin-like
Domain	IPR033989	CD209-like, C-type lectin-like domain
Family	IPR050828	C-type lectin and matrix domain-containing protein
Homologous_superfamily	IPR016186	C-type lectin-like/link domain superfamily
Homologous_superfamily	IPR016187	C-type lectin fold