Gene
serpinf2a
- ID
- ZDB-GENE-060822-1
- Name
- serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a
- Symbol
- serpinf2a Nomenclature History
- Previous Names
-
- serpinf2
- serpinf2l (1)
- wu:fd57d08
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in alpha-2-plasmin inhibitor deficiency. Is expressed in liver. Orthologous to human SERPINF2 (serpin family F member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Cheng et al., 2006
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| alpha-2-plasmin inhibitor deficiency | Alliance | Alpha-2-plasmin inhibitor deficiency | 262850 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Serpin domain | Serpin family | Serpin superfamily | Serpin superfamily, domain 1 | Serpin superfamily, domain 2 |
|---|---|---|---|---|---|---|
|
UniProtKB:F6NQ58
|
457 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
serpinf2a-201
(1)
|
Ensembl | 1,805 nt |
Interactions and Pathways
No data available
Plasmids
No data available