Gene

crb3a

ID

ZDB-GENE-060610-2

Name

crumbs homolog 3a

Symbol

crb3a Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Involved in inner ear auditory receptor cell differentiation and regulation of non-motile cilium assembly. Predicted to localize to integral component of membrane. Is expressed in brain; eye; gut; otic vesicle; and photoreceptor cell. Orthologous to human CRB3 (crumbs cell polarity complex component 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from Hazime et al., 2017
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With crb3a Human Ortholog

No data available

Associated With crb3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

No data available

Domain Details Per Protein

Protein	Length
UniProtKB:Q1A5L0 InterPro	109

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	crb3a-201 (1) Ensembl	Ensembl		3,405 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab2-crb		crb1 crb2a crb2b crb3a crb3b		Rabbit	IHC		2
Ab1-crb		crb1 crb2a crb2b crb3a crb3b		Rabbit	IHC WB		5

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations