Gene
pals1b
- ID
- ZDB-GENE-060531-2
- Name
- protein associated with LIN7 1, MAGUK p55 family member b
- Symbol
- pals1b Nomenclature History
- Previous Names
-
- im:7140055
- mpp5b
- ponli (1)
- sb:eu974
- si:ch211-105d18.1
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to be involved in several processes, including establishment or maintenance of epithelial cell apical/basal polarity; morphogenesis of an epithelium; and protein localization to plasma membrane. Predicted to be located in apical plasma membrane and bicellular tight junction. Predicted to be active in adherens junction and plasma membrane. Is expressed in eye; retinal cone cell; and retinal photoreceptor layer. Orthologous to human PALS1 (protein associated with LIN7 1, MAGUK p55 family member).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020590 | Guanylate kinase, conserved site |
| Domain | IPR001452 | SH3 domain |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR004172 | L27 domain |
| Domain | IPR008144 | Guanylate kinase-like domain |
| Domain | IPR008145 | Guanylate kinase/L-type calcium channel beta subunit |
| Domain | IPR014775 | L27 domain, C-terminal |
| Domain | IPR015145 | L27-N |
| Domain | IPR035601 | MPP5, SH3 domain |
| Family | IPR050716 | Membrane-associated guanylate kinase |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
| Homologous_superfamily | IPR036892 | L27 domain superfamily |
Domain Details Per Protein
| Protein | Length | Guanylate kinase, conserved site | Guanylate kinase-like domain | Guanylate kinase/L-type calcium channel beta subunit | L27 domain | L27 domain, C-terminal | L27 domain superfamily | L27-N | Membrane-associated guanylate kinase | MPP5, SH3 domain | PDZ domain | PDZ superfamily | P-loop containing nucleoside triphosphate hydrolase | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:D3X469
|
639 | ||||||||||||||
|
UniProtKB:A8DZ97
|
363 | ||||||||||||||
|
UniProtKB:A0A8M3B4D4
|
512 | ||||||||||||||
|
UniProtKB:A0A8M9PP48
|
403 | ||||||||||||||
|
UniProtKB:A0A8M3AL41
|
537 | ||||||||||||||
|
UniProtKB:A0A8M6YU41
|
377 |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-pals1b | polyclonal | Rabbit |
|
3 |
Plasmids
No data available