Gene
pals1b
- ID
- ZDB-GENE-060531-2
- Name
- protein associated with LIN7 1, MAGUK p55 family member b
- Symbol
- pals1b Nomenclature History
- Previous Names
-
- im:7140055
- mpp5b
- ponli (1)
- sb:eu974
- si:ch211-105d18.1
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to be involved in bicellular tight junction assembly and establishment of epithelial cell polarity. Is expressed in eye; retinal cone cell; and retinal photoreceptor layer. Orthologous to human MPP5 (membrane palmitoylated protein 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020590 | Guanylate kinase, conserved site |
| Domain | IPR001452 | SH3 domain |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR004172 | L27 domain |
| Domain | IPR008144 | Guanylate kinase-like domain |
| Domain | IPR008145 | Guanylate kinase/L-type calcium channel beta subunit |
| Domain | IPR014775 | L27 domain, C-terminal |
| Domain | IPR015145 | L27-N |
| Domain | IPR035601 | MPP5, SH3 domain |
| Family | IPR050716 | Membrane-associated guanylate kinase |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
| Homologous_superfamily | IPR036892 | L27 domain superfamily |
Domain Details Per Protein
| Protein | Length | Guanylate kinase, conserved site | Guanylate kinase-like domain | Guanylate kinase/L-type calcium channel beta subunit | L27 domain | L27 domain, C-terminal | L27 domain superfamily | L27-N | Membrane-associated guanylate kinase | MPP5, SH3 domain | PDZ domain | PDZ superfamily | P-loop containing nucleoside triphosphate hydrolase | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:D3X469
|
639 | ||||||||||||||
|
UniProtKB:A8DZ97
|
363 | ||||||||||||||
|
UniProtKB:A0A8M3B4D4
|
512 | ||||||||||||||
|
UniProtKB:A0A8M9PP48
|
403 | ||||||||||||||
|
UniProtKB:A0A8M3AL41
|
537 | ||||||||||||||
|
UniProtKB:A0A8M6YU41
|
377 |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-pals1b | polyclonal | Rabbit |
|
3 |
Plasmids
No data available