Gene

kcnn1b

ID

ZDB-GENE-060503-397

Name

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1b

Symbol

kcnn1b Nomenclature History

Previous Names

kcnn1
sk1 (1)
si:ch211-200a16.1

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to have calmodulin binding activity and small conductance calcium-activated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to localize to neuron projection; neuronal cell body; and plasma membrane. Is expressed in head and nervous system. Orthologous to several human genes including KCNN2 (potassium calcium-activated channel subfamily N member 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kcnn1b Human Ortholog

No data available

Associated With kcnn1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004178	Calmodulin-binding domain
Domain	IPR013099	Potassium channel domain
Family	IPR015449	Potassium channel, calcium-activated, SK
Homologous_superfamily	IPR036122	SK, calmodulin-binding domain superfamily

Domain Details Per Protein

Protein	Length	Calmodulin-binding domain	Potassium channel, calcium-activated, SK	Potassium channel domain	SK, calmodulin-binding domain superfamily
UniProtKB:A0A0R4IC13 InterPro	547
UniProtKB:A0A8M2BE84 InterPro	811
UniProtKB:A0A8M9Q9S4 InterPro	609
UniProtKB:Q1LY45 InterPro	235
UniProtKB:A0A8M9Q3J1 InterPro	814

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	kcnn1b-201 (1) Ensembl	Ensembl	1,180 nt	Select Tool ZFIN BLAST
mRNA	kcnn1b-202 (1) Ensembl	Ensembl	1,800 nt	Select Tool ZFIN BLAST
mRNA	kcnn1b-203 (1) Ensembl	Ensembl	1,410 nt	Select Tool ZFIN BLAST
mRNA	kcnn1b-204 (1) Ensembl	Ensembl	1,644 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-kcnn1b	polyclonal	kcnn1b		Goat	IHC	Santa Cruz Biotechnology, Inc.	2

Plasmids

Addgene:164957

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations