Gene

dmc1

ID

ZDB-GENE-060331-93

Name

DNA meiotic recombinase 1

Symbol

dmc1 Nomenclature History

Previous Names

zgc:136628

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to have DNA binding activity; DNA-dependent ATPase activity; and recombinase activity. Predicted to be involved in DNA recombination; chromosome organization involved in meiotic cell cycle; and response to ionizing radiation. Predicted to localize to condensed nuclear chromosome. Is expressed in ovary. Orthologous to human DMC1 (DNA meiotic recombinase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dmc1 Human Ortholog

No data available

Associated With dmc1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR013632	DNA recombination and repair protein Rad51-like, C-terminal
Domain	IPR020587	DNA recombination and repair protein RecA, monomer-monomer interface
Domain	IPR020588	DNA recombination and repair protein RecA-like, ATP-binding domain
Family	IPR011940	Meiotic recombination protein Dmc1
Family	IPR016467	DNA recombination and repair protein, RecA-like
Homologous_superfamily	IPR010995	DNA repair Rad51/transcription factor NusA, alpha-helical
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase