Gene
cxcr3.1
- ID
- ZDB-GENE-060130-38
- Name
- chemokine (C-X-C motif) receptor 3, tandem duplicate 1
- Symbol
- cxcr3.1 Nomenclature History
- Previous Names
-
- CXCR3ab (1)
- dr-chr16-CXCR3-41.8-EK27498
- sb:eu378
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable C-C chemokine binding activity and C-C chemokine receptor activity. Predicted to be involved in several processes, including calcium-mediated signaling; cell chemotaxis; and positive regulation of cytosolic calcium ion concentration. Predicted to act upstream of or within several processes, including G protein-coupled receptor signaling pathway; angiogenesis; and regulation of leukocyte migration. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Is expressed in macrophage. Human ortholog(s) of this gene implicated in asthma. Orthologous to human CXCR3 (C-X-C motif chemokine receptor 3).
- Genome Resources
- Note
-
Removing ENSDARG00000078177 as there does not appear to be a good match with the T2T assembly. It is possible that this is a haplotype. Moving the ID to a separate gene ZDB-GENE-240624-1.
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu378 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | C-C chemokine receptor type 1-9-like | Chemokine receptor family | CXC chemokine receptor 3 | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|---|---|
|
UniProtKB:F1Q6R0
|
367 | |||||
|
UniProtKB:A4QNU5
|
357 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cxcr3.1-201
(1)
|
Ensembl | 2,615 nt | ||
| mRNA |
cxcr3.1-202
(1)
|
Ensembl | 2,821 nt |
Interactions and Pathways
No data available
Plasmids
No data available